| 학회 |
한국화학공학회 |
| 학술대회 |
2021년 봄 (04/21 ~ 04/23, 부산 BEXCO) |
| 권호 |
27권 1호, p.528 |
| 발표분야 |
생물화공 |
| 제목 |
An efficient antibacterial approach utilizing glucose oxidase/magnetic nanoparticles/copper nanoflowers |
| 초록 |
Bacterial contamination has been considered as a pressing issue since it provokes various problems ranging from bacterial infection, food spoilage to environmental pollution such as biofouling. Glucose oxidase (GOx)-copper hybrid nanoflowers embedded with amine-functionalized magnetic nanoparticles (NH2-MNPs), denoted as ‘MNP-GOx NFs’, which are non-toxic and effective antibacterial agents have been successfully synthesized. Positively-charged NH2-MNPs and negatively-charged GOx molecules are first interacted via electrostatic attraction which can be controlled by adjusting buffer pH, followed by the addition of copper(II) sulfate to induce the blooming of nanoflowers (MNP-GOx NFs) after 3-day incubation at room temperature. The NFs exhibited competent antibacterial activity by forming H2O2 from GOx-catalyzed glucose oxidation. In particular, 99.9% killings of Staphylococcus aureus and Escherichia coli are achieved after 3-hour treatment. MNP-GOx NFs have opened up a tremendous promise for their applications in a variety of fields such as biosensors, biofuel cells and bioconversion as well as bacterial de-contamination. |
| 저자 |
NGUYEN QUYNH HUONG1, 이인선2, 김중배2, 김문일1
|
| 소속 |
1가천대, 2고려대 |
| 키워드 |
생물화학공학 |
| E-Mail |
|
| 원문파일 |
초록 보기 |
