| 초록 |
Although brown macroalgae holds an enormous potential as an alternative feedstock, its utilization by conventional microbial platforms has been limited due to the inability to metabolize one of the principal sugars, alginate. Here, we isolated Vibrio sp. dhg, a novel, fast-growing bacterium that can efficiently assimilate alginate. Based on systematic characterization of the genomic information of Vibrio sp. dhg, we were able to develop a genetic toolbox for its engineering, and successfully demonstrated its ability to rapidly produce a broad spectrum of chemicals (ethanol, 2,3-butanediol, and lycopene) from brown macroalgae sugar mixtures with a high productivity and yield. Collectively, the Vibrio sp. dhg strain is a powerful platform for the conversion of brown macroalgae sugars whose usage will dramatically accelerate the production of value-added biochemicals. |
