| 초록 |
Chitosan, a polycationic natural polymer, is considered to be a promising candidate for hydrogel synthesis, and the solubility of chitosan in low pH environment is well-defined. It is also a natural product extracted from mussels and crustacean shell waste which are originally secondary derivatives of chitin. In this study, modified catechol chitosan (CCS) for an eminent level for substitution was synthesized in place on research those intricate connections between Fe3+ and catechol under different pH conditions. The ratios of catechol, chitosan and other reagents decide the structure of the hydrogel. The gel formation is then well-maintained by dual cross-linking through electrostatic interactions between CCS and Fe3+ along with covalent catechol-coupling-based coordinate bonds. The hydrogels demonstrated enhanced mechanical strength and cohesiveness at higher pH and EDTA treatment is a key factor in modifying uniform hydrogel structure at different conditions. |
