| 학회 |
한국공업화학회 |
| 학술대회 |
2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
22권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Facile one-pot preparation of amine-functionalized and angular-shaped superparamagnetic iron oxide nanoparticles as multimodal nanoprobe |
| 초록 |
A simple preparation of water-dispersible angular-shaped and amine-functionalized super-paramagnetic iron oxide nanoparticles (A-SPIONs) is demonstrated in this research. A-SPIONs was synthesized via heating iron (Ⅲ) acetylacetonate in a mixed solvents of polyethyleneglycol (PEG) and branched polyetheyleneimine (b-PEI). In addition, b-PEI controlled overall morphologies of A-SPIONs to produce polyhedral nanocrystals with the aid of added halide ions and provided amine moieties. The angular-shaped iron oxide nanoparticles also exhibited high relaxivity for magnetic resonance imaging (MRI) originated from the high magnetization. Cy 5.5 dye-functionalized A-SPIONs (Cy5.5@A-SPIONs) were prepared and serial experiments were conducted to investigate fluorescence imaging applications. According to these results, the A-SPIONs are expected to have potentials in bimodal imaging application. |
| 저자 |
홍휘찬, 박원철
|
| 소속 |
서울대 |
| 키워드 |
iron oxide; amine functionalization; bimodal imaging
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| E-Mail |
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