화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center))
권호 24권 1호
발표분야 [콜로이드·계면화학] 콜로이드계면화학의 최신 연구동향 및 응용
제목 Colloid-inspired nanoplasmonic biosensing strategies for antiviral peptide evaluation
초록 Surface-based nanoplasmonic sensors are powerful tools to characterize biomacromolecular interactions with biomembrane-mimicking platforms. In this talk, I will discuss how nanoparticle- and nanohole-based nanoplasmonic sensing platforms can be utilized to characterize the mechanistic properties of a membrane-active, antiviral peptide. Three examples will be covered: (i) peptide-induced rupture of a close-packed lipid vesicle adlayer on titanium oxide-coated gold nanodisks; (ii) peptide-induced rupture of individual virus-like particles within long-range-ordered, polymer-functionalized gold nanoholes; and (iii) peptide-induced disruption of positively curved membranes in short-range-ordered, silica-coated gold nanoholes.
저자 Joshua A. Jackman
소속 성균관대
키워드 nanoplasmonic; nanofabrication; biosensing; lipid membrane; antiviral peptide
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