| 학회 |
한국재료학회 |
| 학술대회 |
2010년 가을 (11/11 ~ 11/12, 무주리조트) |
| 권호 |
16권 2호 |
| 발표분야 |
D. Health and Biological Materials(생체 및 의용재료) |
| 제목 |
Fabrication of Artificial Cortical Bone using bioceramics |
| 초록 |
In this study, small bone like continuously porous TCP/ TCP-(t-ZrO2)/t-ZrO2 composites with a central channel were fabricated using a multi-pass extrusion process. Hydroxyapatite (HAp) powder was used as the raw powder which was changed into the α-tricalcium phosphate phase (α-TCP) at a sintering temperature of 1500˚C. The external diameter was approximately 10 mm and inside a cylindrical hollow space was made for spongy bone. The frame region contained numerous micro-channels that extended through the entire length of the frame. The channeled frame region had a multilayer microstructure with a TCP/ TCP-(t-ZrO2)/t-ZrO2. The outer layer consisted of TCP to increase the biocompatibility. The material properties for implanting in body were characterized and micro-structural analysis was carried out. Furthermore, the cytotoxicity and cell attachment and spreading behavior were evaluated by the MTT assay and one cell morphology using osteoblast like MG-63 cells. |
| 저자 |
Dongwoo Jang, Minsung Kim, Byong-Taek Lee
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| 소속 |
순천향의과대 |
| 키워드 |
: bioceramics; extrusion; artificial bone; microstructure; calcium phosphate
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| E-Mail |
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