화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2003년 가을 (10/24 ~ 10/25, 한양대학교)
권호 9권 2호, p.1864
발표분야 분리기술
제목 Application of one-column analogue to a four-zone simulated moving bed for amino acids separation
초록 The separation of binary mixture in an one-column chromatograph with recycle that is analogous to a four-zone simulated moving bed (SMB) was studied. The basic principle of the process is identical to a four-zone SMB. The one-column process consists of one adsorption column and four tanks instead of four columns in four-zone SMB (1-1-1-1). A systematic experiment for one-column process was carried out for the separation of two amino acids, phenylalanine and tryptophan. The operating parameters of one-column process were obtained from equilibrium theory. The computer simulations were done by Aspen ChromatographyTM. The experimental results of one-column process show good agreements with simulation results. The experimental product purity of the one-column process were 89.9% and 85.1% for phenylalanine and tryptophan, respectively, while 92.1% and 85.7% for the simulation results. The recovery yields of the one-column process were 93.7% and 77.3% for phenylalanine and tryptophan, respectively, while 93% and 84.7% for the simulation results. The one-column process would be useful to reconstruct an existing conventional batch chromatography.
저자 구윤모1, 김영식1, 이종호1, Phillip C. Wankat2
소속 1인하대, 2School of Chemical Engineering
키워드 11
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