| 초록 |
In nature, a variety of water-insoluble materials are biologically synthesized by water-soluble precursors. This water-basis, environment-friendly biochemical strategy evolutionally optimized in nature can solve problems in present un-sustainable society caused by petroleum-based olefin materials. Here, we aim at the spontaneous formation of water-insoluble, biocompatible microfilms from water-soluble polymers without using any additives inspired by insect cuticle formation. Water-soluble chitosan-catechol polymeric precursor is spontaneously converted to flexible thin films by the simple dehydration process. Considering most water-soluble polymers form powders when dehydrated, the preparation of mechanically robust, water-insoluble, flexible chitosan film is the completely unexpected result. This film can be used as a conventional bag similar to polyvinyl one and is multifunctional, biocompatible material for drug delivery depots and tissue engineering applications. |
