| 학회 |
한국공업화학회 |
| 학술대회 |
2014년 가을 (11/12 ~ 11/14, 엑스코(대구)) |
| 권호 |
18권 2호 |
| 발표분야 |
생물공학-포스터 |
| 제목 |
A cell-instructive bioactive hydrogel with micro-channeled piezoelectric membrane |
| 초록 |
The hydrogel has been studied for various applications including controlled drug delivery, tissue engineering, micro-scale actuators and microfluidic flow control. This study demonstrates that a new method to align and control spatial organization of bioactive hydrogel into micro-channels of a poly(vinylidene fluoride) membrane and guide growth direction and spacing of living cells. This integrated bioactive hydrogel system was prepared by fabricating a micro-channeled PVDF membranes and subsequently filling micro-channels with a hydrogel of biologically active collagen. The micro-channeled PVDF was fabricated by inducing the directional growth of cylindrical solvent crystals at a controlled freezing speed and removing them by lyophilization. Finally, the aligned micro-channels were filled with a collagen hydrogel in a vacuum for guiding and leading the myoblasts into the patterned myotubes. |
| 저자 |
조성우1, 조윤나1, 이솔이1, 김희진1, Minkyung Lee2, Hyunjoon Kong2, 정재현1
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| 소속 |
1숭실대, 2Univ. of Illinois at Urbana-Champaign |
| 키워드 |
piezoelectric membrane; collagen; myotube
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| E-Mail |
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