| 학회 |
한국고분자학회 |
| 학술대회 |
2013년 봄 (04/11 ~ 04/12, 대전컨벤션센터) |
| 권호 |
38권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Preparation and characterization of pH-sensitive sodium alginate/poly(vinyl alcohol)/bentonite blend beads for controlled release of diclofenac sodium |
| 초록 |
In order to enhance the drug entrapment efficiency and improve the swelling behaviors of drug delivery system, Ca2+ crosslinking technique was used to prepare sodium alginate/ poly(vinyl alcohol)/betonite beads. Beads of different compositions were prepared by varying the amount of poly(vinyl alcohol) and bentonite and characterizing it by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction(XRD). The swelling and pH-sensitive properties of the beads were investigated, and the drug loading and controlled release properties of the beads were also evaluated using diclofenac sodium as the model drug. |
| 저자 |
정경희, 강세미, 이재호, 황대연, 정영진
|
| 소속 |
부산대 |
| 키워드 |
Alginate; Poly(vinyl alcohol); Bentonite; Controlled release
|
| E-Mail |
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