| 초록 |
Late thrombosis has remained to be a problem, even though drug-eluting stent (DES) has solved partially the drawback of restenosis. Late thrombosis is known to be caused by polymers coated for the control of drug release rate. Thus, our interest has been focused on reducing polymer amount coated on stents. In this study, we have produced a cobalt oxide (Co3O4) nanowire array on the surface of Co-Cr alloy. Unlike existing methods, we prepared Co3O4 nanowire-arrayed Co-Cr surface, which is being investigated as one of the promising material for lithium-ion battery electrode. Co3O4 nanowires were produced by hydrothermal method. The resulting nanostructure was observed by SEM and XRD for confirming nanostructure. And the profiles of release rate were monitored after coating with drug using electrospray. Therefore, Co3O4 nanowire arrayed surface may be a promising strategy for developing biocompatible DES. |
