| 학회 |
한국재료학회 |
| 학술대회 |
2016년 가을 (11/16 ~ 11/18, 경주 현대호텔) |
| 권호 |
22권 2호 |
| 발표분야 |
B. 나노화학/바이오 재료 분과 |
| 제목 |
Label-free Electrochemical Detection of Virus and Bacteria Particles Using Gap Device |
| 초록 |
In this study, electrochemical analysis using nano/micro gap device has been applied for label-free detection of virus and bacteria particles. Vaccinia virus and Streptococcus Pneumoniae were employed as a target particles. The gap distance plays a most important role for clear recognition of electrochemical signal changes because interruption of electron transfer between facing electrodes can be occurred by target particles which were immobilized on the gap area. Gap distances were controlled by surface-catalyzed chemical deposition after conventional photo-lithography according to size of target biomolecules. Furthermore, amplified electrochemical signal by redox cycling of ferri/ferrocyanide as an electro-active probe leads to detect low concentration of each target with a significant signal changes. The result of electrochemical signal changes can be considered as a simple indicator for sensitive detection of biologically interfacing substances in the gap area. |
| 저자 |
Dae Keun Park1, Soohyun Kim2, Kum-Hee Yun1, Hannah Pyo2, Aeyeon Kang1, Dae Hee Kim2, Cho Yeon Lee1, Wan Soo Yun2
|
| 소속 |
1Department of Chemistry, 2Sungkyunkwan Univ. |
| 키워드 |
<P>Biosensor; Label-free detection; Gap Device; Vaccinia virus; Streptococcus Pneumoniae</P>
|
| E-Mail |
|
