| 학회 |
한국고분자학회 |
| 학술대회 |
2006년 봄 (04/06 ~ 04/07, 일산킨텍스) |
| 권호 |
31권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Biomineralization of Synthetic Hydrogel Scaffolds for 3-Dimensional Bonelike Composites |
| 초록 |
Biomimetic synthetic approaches have been widely employed to develop bonelike composite materials with improved mechanical properties and enhanced biocompatibility. In this work, using a biomineralization approach, we develop synthetic organic-inorganic composites based on PEG-based hydrogels containing phosphate anionic ligands as apatite nucleators. We employed the urea-mediated solution precipitation technique for biomineralization of hydrogels. The apatite grown on the surface and interior of the hydrogels was similar to biological apatities. With increasing the content of phosphate groups, the apatite formation was found to be more effective. The evaluation of mineralized hydrogel composites for cell adhesion and proliferation are under way. Acknowledgement. This research was supported by a grant (code #: 05K1501-01510) from 'Center for Nanostructured Materials Technology' under '21st Century Frontier R&D Programs' of the Ministry of Science and Technology, Korea. |
| 저자 |
김찬우1, 최형우2, 김경자1, 이상천1
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| 소속 |
1요업(세라믹)기술원 생체재료팀, 2요업(세라믹)기술원 생체재료팀 / 연세대 |
| 키워드 |
Biomineralization; hydrogels; anionic ligands
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| E-Mail |
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