화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU))
권호 22권 2호
발표분야 생체재료_포스터
제목 Effects of Incorporation of Ceramic Particles into Naturally-derived Polymeric Films on Osteoblast Responses
초록 Naturally derived polymers such as chitosan and collagen are highly biocompatible and degradable by enzymatic activity, which confers strong capability of the polymers for the usage in bone substitutes. The surface properties of the materials, however, can be crucial to determine the cellular responses, i.e. adhesion, proliferation, and differentiation. In this study, we prepared the chitosan/collagen complex film with incorporated ceramic particles. The ceramic inclusion also induced significant changes in osteoblastic responses including adhesion, proliferation, and differentiation. Our observation illustrated that the ceramic particle inclusion significantly improved osteoblastic responses, demonstrating that this technique can be further applied for the improvement of surface modification of bone substitutes.
저자 김정헌, 김민정, 박은현, 송민주, 이민선, 이병학, 임예람, 이우걸
소속 단국대
키워드 Keywords: Chitosan; collagen; CaP; drug; film
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