화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2016년 가을 (10/19 ~ 10/21, 대전컨벤션센터)
권호 22권 2호, p.2573
발표분야 바이오메디컬 소재 및 응용 한·일 국제 심포지엄(특별 심포지엄)
제목 Optical cell manipulation using biomaterial-based photodegradable hydrogels
초록 We have developed a photocleavable crosslinker for preparing photodegradable hydrogels by means of a one-step mixing reaction between the crosslinker and biocompatible polymers. We could control the chemical property of the photodegradable hydrogel by choosing the base polymer. We could prepare the biomaterial-based photodegradable hydrogels, on which cells adhered, and in which cells were encapsulated. So far, we have demonstrated cell separation from three-dimensional culture environment, cell micropatterning, and perfusion culture in the microfluidic devices. These studies will create new opportunities as novel the cell manipulation technologies in science and industry.
저자 Shinji Sugiura1, Toshiyuki Kanamori2
소속 1Biotechnology Research Institute for Drug Discovery, 2National Institute of Advanced Industrial Science and Technology (AIST)
키워드 Cell manipulation; Cell separation; Cell micropatterning; Photodegradable hydrogel; Gelatin
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