| 학회 |
한국화학공학회 |
| 학술대회 |
2009년 봄 (04/23 ~ 04/24, 광주 김대중컨벤션센터) |
| 권호 |
15권 1호, p.866 |
| 발표분야 |
재료 |
| 제목 |
Photothermal Cell Lysis via Plasmonic Gold Nanostructures |
| 초록 |
Metal nanostructures such as nanoparticles, nanoshells and nanocages have been focused on the optical properties which make it possible to detect chemical/biological substances. Here, we investigated the optical (Localized Surface Plasmon Resonance (LSPR)) and physical properties of gold nanostructures for the cell lysis. Various cells have been lysed due to the heat generated by light radiation on plasmonic metal nanostructures, known as ‘photothermal effect’. The photothermal effect occurs strongly on metal nanostructures when the incident light is resonant with surface plamon. The gold nanostructures were fabricated via colloidal lithography and each cell was put into a gold nanostructure by centrifugal force. Finally, the cells captured in the gold nanostructures were lysed by using tunable laser, Ti;Sapphire laser with surface plasmon wavelength about 800 nm. It enables us to analyze the single cell in a microfluidic chip without any reagents or equipment. |
| 저자 |
김수경1, 허철준1, 최종영2, 심재원1, 장세규3, 서태석4, 양승만2
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| 소속 |
1한국과학기술원 생명화학공학과 / 광자유체집적소자연구단, 2한국과학기술원 생명화학공학과, 3Univ. of California, 4Santa Barbara |
| 키워드 |
Photothermal effect; LSPR; Cell lysis; Plasmonic structures
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| E-Mail |
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| 원문파일 |
초록 보기 |
