학회 |
한국화학공학회 |
학술대회 |
2021년 가을 (10/27 ~ 10/29, 광주 김대중컨벤션센터) |
권호 |
27권 2호, p.1595 |
발표분야 |
미립자공학 |
제목 |
Controlled synthesis of cobalt ferrite magnetic nanoparticles for hyperthermia-based treatments |
초록 |
The magnetic cobalt ferrite (CoFe2O4) nanoparticles have attracted considerable attention in biomedical applications because of their specific magnetic properties. The CoFe2O4 nanoparticles were synthesized by solvothermal method using oleic acid as a surfactant. The morphology of CoFe2O4 nanoparticles could be controlled by adjusting the oleic acid concentration. The oleic acid-coated CoFe2O4 nanoparticles are well dispersible in non-polar organic media and not stable in aqueous phase. Therefore, we tried to prepare hydrophilic nanoparticles by coating their surface with citric acid for biomedical applications. We investigated the potential of citric acid-coated (CA-CoFe2O4) nanoparticles in hyperthermia treatment by magnetic heating instrument using an alternating magnetic field. The specific absorption rate (SAR) of CoFe2O4 nanoparticles was calculated based on experimental studies. Our results showed that the higher magnetic field strength resulted in faster heating rate. Usually, the smaller CoFe2O4 nanoparticles have the higher value of SAR and also higher hyperthermia efficiency in this study. |
저자 |
Duong Thi Hong Diu1, 윤상혁2, 김교선2
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소속 |
1Kangwon National Univ., 2강원대 |
키워드 |
미립자제조; 미립자분석; 미립자응용
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E-Mail |
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원문파일 |
초록 보기 |