| 학회 | 한국공업화학회 |
| 학술대회 | 2013년 봄 (05/01 ~ 05/03, ICC JEJU) |
| 권호 | 17권 1호 |
| 발표분야 | 포스터-고분자 |
| 제목 | Preparation of thermal responsive cubosomes containing gold nanoparticles. |
| 초록 | Conventional gold nanoparticles can hardly accommodate therapeutics and we designed poly(N-isopropylacrylamide_co_ocatecyl acrylate) (P(NIPAM_co_ODA))-immobilized and gold nanoparticle-loaded cubosomes, which can readily water-soluble drugs. Gold nanoparticles were formed in the water channels of cubosomes by including stearic acid(SA), which can absorb AU2+ on interfaces of the cubosomes and water. A thermo sensitive polymer have a lower critical solution temperature (LCST), which is water-soluble and takes an extended form under the LCST and takes a contracted form when the temperature is increased above the LCST. Irradiating a laser, gold nanopariticles will generate heat and the themperature of the cubosomes will be increased. Therefore, P(NIPAM_co_ODA) immobilized in the water channels was phase transition and it will control the release of drugs from the cubosomes. |
| 저자 | 조창현, 심성보, 김진철 |
| 소속 | 강원대 |
| 키워드 | thermal senstive; P(NIPAM_co_ODA); gold nanoparticle; cubosome |
