| 학회 |
한국고분자학회 |
| 학술대회 |
2018년 가을 (10/10 ~ 10/12, 경주컨벤션센터) |
| 권호 |
43권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Water soluble molybdneum sulfide/molybdneum oxide (MoS2/MoOx) hybrid nanocomposite for efficient phothermal and hypoxia reducible cancer therapy |
| 초록 |
Current cancer therapy strategies are inefficient as they fail to acknowledge the importance of tumor microenvironments (TME). Tumor hypoxia is a distinctive TME around solid tumors, which is responsible for cancer proliferation and metastasis. They are also responsible for inefficient radiotherapy and can also generate cancer drug resistance. Here, we report the fabrication of water soluble molybdneum sulfide/molybdneum oxide (MoS2/MoOx) hybrid nanocomposite for efficient phothermal and hypoxia reducible cancer therapy. A novel snapfreeze-thaw method was opted for the synthesis of MoS2/MoOx nanocomposite. The results show that the developed nanomaterials were able to generate heat under NIR irradiation. We further confirmed the ability of MoS2/MoOx hybrid to catalytically degrade the H2O2 and generate oxygen. Our studies conclude that the developed hybrid nanomaterial can be beneficial for diverse biomedical applications. |
| 저자 |
Vishnu Revuri1, 김혜민2, 안정만1, 이용규2
|
| 소속 |
1Korea National Univ. of Transportation, 2Department of Chemical and Biological Engineering |
| 키워드 |
Photohtermal Therapy; hydrogen Peroxide; biosensor; hypoxia; molybdenum
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| E-Mail |
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