| 초록 |
Semiconductor quantum dots (QDs) have many advantages including a high quantum yield (QY), high fluorescent signal, photo-stability and narrow emission spectrum, compared to a traditional fluorescent dye. However, After the surface modification of QDs for bio-applications, QY is getting significantly lower. In this study, we describe the water-soluble multi shell QDs with high quantum yield. This multi-shell QDs show a strong fluorescence signal compared to established single shell QDs. Besides, multi shell QDs indicate a high stability in a strong pH range. After the surface modification for bio-applications, multi-shell QDs maintain slightly reduced QY. In comparison with single shell QDs, multi shell QDs were discovered a strong fluorescence as feature in vitro and in vivo. This water-soluble multi shell QDs, which surface modified possible one, have a great potential for practical bio-imaging. |
