| 초록 |
A diethylstilbestrol (DES) imprinted mesoporous silica particle was prepared by a sol-gel reaction. Molecular imprinting is a process of introducing molecular recognition sites into a cross-linked matrix. Molecularly imprinted materials have potential uses in applications such as chemical sensors, catalysts, and membranes for separating toxic chemicals. The mesoporous silica particle was synthesized by a sol-gel reaction of TEOS and triethoxysilane-DES (template) complex in an aqueous solution of CTAB. The triethoxysilane-template complex was synthesized by the reaction of the triethoxysilane compound having an isocyanate group and DES having phenol moieties, in which the template was attached to the monomer via a thermally reversible urethane bond. After removing the template molecules, the specific recognition ability of the silica particle to the DES and its structural analogues was investigated by reverse phase HPLC analysis. |
