| 학회 | 한국고분자학회 |
| 학술대회 | 2005년 봄 (04/14 ~ 04/15, 전경련회관) |
| 권호 | 30권 1호, p.26 |
| 발표분야 | 의료용 주입형 하이드로젤 |
| 제목 | Thermo-responsive Pluronic Nanogels |
| 초록 | Pluronic nanogels crosslinked with heparin were newly synthesized by modified emulsification/solvent evaporation method. Preactivated pluronic F-127 with p-nitrophenyl chloroformate was dissolved in dichloromethane. This organic phase was emulsified to nanoparticular size in water by sonication. Activated pluronic F-127 in this emulsion reacted with residual amine of heparin in water, and pluronic nanogels were formed. Pluronic nanogels exhibit a thermally responsible swelling and shrinking behavior and a sharp volume transition over the temperature range of 25 – 33 oC. The reversible volume transition of pluronic nanogels was caused by the micellization and demicellization of cross-linked pluronic polymer chains within the nanogel structure in response to temperature. Fig. 1. Temperature responsive size change of Pluronic nanogel |
| 저자 | 최승호, 박태관 |
| 소속 | 한국과학기술원 |
| 키워드 | Pluronic; Nanogels |
