| 초록 |
L3-phase of 3D-interconnected nanoporous silica L3 phase has been developed to smart drug delivery materials were based on interpenertrating network of thermosensitive poly(N-isoproptlacrylamide) gels and tailored nanoporous silica. A sustainable positive thermo-responsive drug release profile is obtained. When the temperature rises, the polymer gel shrinks, squeezing the drug into the porous channels, and at the same time, opening the pore to the outside media. The drug slowly diffuses out of the porous channels. The overall release rate can be adjusted by changing the composition of the nanogel. |
