| 학회 |
한국공업화학회 |
| 학술대회 |
2008년 가을 (11/12 ~ 11/14, ICC 제주) |
| 권호 |
12권 2호 |
| 발표분야 |
고분자 |
| 제목 |
Development of gamma-irradiated PVA hydrogels reinforced with shikonin as wound healing |
| 초록 |
Shikonin, a substance originally isolated from the root of the Chinese plant that has been used as an ointment for wound healing, was thus applied to reinforce the therapeutic effect of PVA based hydrogels prepared by gamma irradiation.We evaluated the accelerating effect of both substances and compared the histological changes on the proliferation on normal and punch wounds in rats.The hydrogels treated with shikonin significantly accelerated healing of wounds, as measured by wound contraction compared to controls in rats.These results suggest that the treatment of PVA hydrogels with shikonin has a therapeutic effect on excision wound dressing. |
| 저자 |
권희정1, 임윤묵2, 안성준2, 김해경2, 윤민호2, 박종석2, 노영창2
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| 소속 |
1KAIST / 한국원자력(연), 2한국원자력(연) |
| 키워드 |
Gamma Irradiation; Shikonin; PVA Hydrogel; Wound healing
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| E-Mail |
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