| 학회 | 한국고분자학회 |
| 학술대회 | 2002년 가을 (10/11 ~ 10/12, 군산대학교) |
| 권호 | 27권 2호, p.191 |
| 발표분야 | 의료용 고분자 부문위원회 |
| 제목 | Preparation and Characterization of Novel Porous SIS-impregnated Alginate Scaffold |
| 초록 | Alginate, a naturally occurring biopolymer extracted from brown algae (kelp), has good biocompatibility and biodegradability. Alginate can be ionically crosslinked by the addition of divalent cations in aqueous solution. Porcine small intestinal submucosa (SIS) has been investigated as a source of collagenous tissue with the potential to be used as a biomaterial because of its inherent strength and biocompatibility. In order to develop a tissue engineered scaffold, porous matrices containing alginate and SIS were fabricated by freeze drying method at -20℃. We observed that SIS/alginate scaffolds were highly porous with good interconnection of the pore structure. SIS/alginate scaffold has been characterized by SEM, mercury porosimeter, DSC, swelling test, and so on. We evaluated the adherence of NIH/3T3 into an SIS/alginate scaffolds. In conclusion, it seems that SIS plays on important role of SIS/alginate scaffolds for tissue engineering. Acknowledgment: This work was supported by KMOCIE (N11-A08-1402-05-2-3). |
| 저자 | 장지욱1, 김인영2, 이상진*3, 강길선**, 이 봉, 이해방* |
| 소속 | 1부경대, 2*한국화학(연), 3**전북대 |
| 키워드 | small intestine submucosa; alginate; scaffold |
