| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 가을 (10/09 ~ 10/10, 일산킨텍스) |
| 권호 |
33권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Injectable, porous, biodegradable microspheres for stem cell tissue engineering |
| 초록 |
We studied the use of biodegradable porous microspheres as cell cultivation carriers and injectable scaffolds for tissue regeneration. Highly open-porous microspheres were fabricated using poly(D,L-lactide-co-glycolide) by a novel single emulsion-phase separation technique. The porous microspheres were used as scaffolds to form cellular aggregates of human mesenchymal stem cells. The cellular aggregates were cultured for 3-D differentiation into adipocytes. To assess the potential of cellular aggregates as injectable adipose tissues for tissue regeneration, aggregates were implanted in vivo by injection. Only the differentiated cellular aggregates resulted in functional tissues expressing the adipocyte-specific phenotype. |
| 저자 |
정현정, 박태관
|
| 소속 |
한국과학기술원 |
| 키워드 |
injectable; porous microsphere; tissue engineering
|
| E-Mail |
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