화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2010년 가을 (10/07 ~ 10/08, 대구 EXCO)
권호 35권 2호
발표분야 기능성 고분자
제목 Synthesis and Characterization of Cross-linked Multi-sensitive Injectable Hydrogel based Pluronic F-127.
초록 A novel multi responsive injectable hydrogel by pH, temperature and reducing agent (DTT) has been developed based on disulfide end-capped Pluronic F-127 polymer (PL-SS-NH2) and benzaldehyde-capped Pluronic F-127 polymer (PL-BA). PL-BA was crosslinked with PL-SS-NH2 and the resultant polymer formed hydrogel containing disulfide bond and benzoic imines bond which were confirmed by H-NMR. Different ratios of the polymer (PL-BA: PL-SS) were crosslinked with each other and among these the polymer ratio 1:1 showed the most efficient formation of multi sensitive hydrogel at lower concentration. Rheological characteristics showed the multi responsiveness against the earlier mentioned stimulus of the developed polymeric hydrogel.
저자 남정아, 박성영
소속 충주대
키워드 Injectable hydrogel; temperature sensitive; pH sensitive; cross-linked; DTT sensitive
E-Mail