화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2008년 봄 (05/09 ~ 05/10, 한양대학교(안산))
권호 12권 1호
발표분야 고분자
제목 Synthesis of amphiphilic ternary MPEG-b-PCL-grafted chitooligosaccharides and their inclusion complexation with α-cyclodextrins
초록 Novel ternary graft copolymers (COS-g-PCL-b-MPEG) were synthesized by N, N’-dicyclohexyl carbodiimide (DCC) coupling reaction between chitooligosaccharide (COS) with MPEG-b-PCL-COOH, which was synthesized via ring-opening polymerization of ε-caprolactone (CL) using methoxy poly(ethylene glycol) (MPEG) as initiator and carboxylated by succinic anhydride. These novel biodegradable tenary graft copolymers and their hydrogels with α-CD have potential to use as drug delivery systems.
저자 호환기, 이종휘
소속 중앙대
키워드 chitooligosaccharide; graft copolymer; micellar behaviour; inclusion complexation; cyclodextrin; hydrogel
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