화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2018년 봄 (04/04 ~ 04/06, 대전컨벤션센터)
권호 43권 1호
발표분야 의료용 고분자 부문위원회 I
제목 Dual pH-Responsive System by Hybrid Gel with Polymer Backbones and DNA Moieties
초록 Polymer has played an important role as an organic material in various fields of research and industry, and its property of responsiveness to stimuli has drawn attention for applications as a smart material. DNA also has been an interesting subject as an organic material itself as well as a programmable code; especially pH-dependent mispairing makes DNA more attractive to examine. Although various studies have been reported to relate these two fields, polymer and DNA still have a good many things to find inbetween. Here, we synthesizes a hybrid gel with polymer and DNA having pH-responsive properties both. This hybrid gel is obtained by sol-gel transition in pH change showing swelling-shrinking behaviors. By this study, we report a new mean of pH-responsive system by the polymer-based DNA hybrid gel suggesting its potential in the fields of controlled drug delivery, sensors, actuators, nanomachine, 3D printing and microfluidics.
저자 김혜진, 오승수, 김진곤
소속 포항공과대
키워드 hybridgel; on-demand; pH-responsive; polymer; DNA
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