| 학회 | 한국화학공학회 |
| 학술대회 | 2013년 가을 (10/23 ~ 10/25, 대구 EXCO) |
| 권호 | 19권 2호, p.1532 |
| 발표분야 | 생물화공 |
| 제목 | Production of GABA(gamma aminobutyric acid)in lab scale bobble column reactor |
| 초록 | Gamma aminobutyric acid(GABA), a four carbon non-protein amino acid, GABA is produced primarily by the enzyme glutamate decarboxylase, which catalyses the irreversible decarboxylastion of glutamate to GABA. GABA has varius physiological functions in animals and humans. GABA is known to be involved in the hypotensive, diuretic, and tranquilizing effects. GABA intake could also help treat various neurological disorders such as seizures, Parkinson’s disease. stiff-man syndrome, and schizophrenia, sleeplessness, depression, and autonomic disorders, chronic alcohol-related symptoms, and have an inhibitory action on cancer cell. Recently, mass production of GABA using lactic acid bacteria has been sturdied using Lactobacillus brevis, Lactococcus lactis, Lactobacillus paracasei. Using lactic acid bacteria has problem to low productivity, quality, and long production time. In this study, 1 M glutamate was conveted to 1 M GABA during 5 hr, using bobble column reactor. |
| 저자 | 김의진, 조하늘, 김은지, 이중헌 |
| 소속 | 조선대 |
| 키워드 | GABA; Monosodium glutamate(MSG); Glutamate decarboxylase(GAD) |
| 원문파일 | 초록 보기 |
