| 학회 |
한국공업화학회 |
| 학술대회 |
2009년 가을 (10/15 ~ 10/16, 서울산업대학교 내 서울테크노파크) |
| 권호 |
13권 2호 |
| 발표분야 |
생물공학(포스터) |
| 제목 |
Preparation of a PEGylated Core-shell Type Polystyrene Resin and Its Application for Solid-Phase Peptide Synthesis |
| 초록 |
We developed PEGlyated core-shell type resin by polyethylene glycol (PEG) conjugation to AM SURETM (aminomethyl surface-layered polystyrene resin) bead. We optimized the reaction condition and characterized its core-shell type structures and properties. This resin bead provided high yield and purity in solid-phase peptide synthesis (SPPS) and the PEG on shell layer reduced nonspecific protein binding property of polystyrene (PS) resin. Furthermore, compared to our previously reported HiCoreTM resin, it gave no auto fluorescence background that could interrupt microscopy fluorescence analysis. |
| 저자 |
박용선, 김미라, 김재희, 이윤식
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| 소속 |
서울대 |
| 키워드 |
PEGlyated core-shell type resin; solid-phase peptide synthesis
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| E-Mail |
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