| 학회 | 한국공업화학회 |
| 학술대회 | 2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션) |
| 권호 | 20권 1호 |
| 발표분야 | 고분자_포스터 |
| 제목 | 메톡시 폴리에틸렌글리콜-올리고펩타이드 복합체의 합성과 생리활성에 관한 연구 (Synthesis and biological activities of the methoxy polyethylene glycol and peptide complexes) |
| 초록 | In this study, methoxy poly ethylene glycol (mPEG) was conjugated to some known anti-wrinkle oligopepetide structures and then their solubility and physiological activity were investigated to develop new medicines and functional cosmetic materials. First, some known anti-wrinkle oligopepetide structures such as tripeptide (Gly–His-Lys: GHK), pentapeptide (Lys–Thr–Thr–Lys–Ser: KTTKS), tripeptide-6 (Gly-Pro-Hyp: GPHyp) and hexapeptide (Glu–Glu–Met–Gln–Arg–Arg: EEMQRR) derivatives were linked to the resin by the solid phase peptide synthesis (SPPS). The longer chain of the amino acid sequence gave the lower yield. |
| 저자 | 정성훈, 채규윤, 김보미, 김후희, 양두리, 임효 |
| 소속 | 원광대 |
| 키워드 | Synthesis; methoxy polyethylene glycol; peptide complexes |
