화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2003년 봄 (04/11 ~ 04/12, 연세대학교)
권호 28권 1호, p.264
발표분야 의료용 고분자 부문위원회
제목 Haemocompatibility tests of vascular grafts
초록 Tests of vascular graft haemocompatibility were performed by in vitro blood perfusion at a venous shear rate. Protein adsorption was performed by employing fibrinogen and albumin as a cell adhesion model protein and a cell-passiving model protein respectively. While the amount of proteins adsorbed on the graft surface was measured by counting the radiolabelled ones, the extent of platelet adhesion was estimated by measuring the surface area of the platelets adhered. The relationship between the amount of adsorbed proteins and adhered platelets was analyzed. In addition to these in vitro tests, in vivo tests were performed in rats and dogs to observe thrombosis and immune repsonses.
저자 정성광;박한기;박영환;강은주;최윤정;홍성화;홍충만;노인섭
소속 서울산업대
키워드 haemocompatibility; vascular graft; proteins adsorption; platelet adhesion
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