| 학회 |
한국재료학회 |
| 학술대회 |
2012년 가을 (11/07 ~ 11/09, 라카이샌드파인 리조트) |
| 권호 |
18권 2호 |
| 발표분야 |
D. 바이오재료(Biomaterials) |
| 제목 |
Natural Bio Polymer Coating on BCP Surface to Evaluate the Comparative Osteogenic Potential |
| 초록 |
In this work, we fabricated BCP disk using uniaxial press machine, and sintered by microwave heating at 1300°C . Then BCP disk was coated with Gelatin, Collagen, Hyaluronic acid, Chondroitin sulphate and Bovine Serum Albumin. Coating morphology and performances were evaluated by SEM. Coating stability and dissolution behavior was observed with exposure to culture media and water uptake measurement. Phase characterizations of the coatings evaluate by were measured fourier transform infrared spectroscopy (FT-IR). Cyto toxycity was carried out by MTT assay. Cell proliferation, ALP activity, Differentiation behavior, Western blot, RT-PCR was carried out to investigate the detail in vitro behavior using adipose derived stem cell. The coated BCP substrates should superior bio-compatibility compared to the bare BCP surface. The study elucidates a comparative analysing of the natural biopolymers as a stimulating agent for bone graft scaffold. |
| 저자 |
Hyoung-Seok Kim1, Swapan Kumar Sakar2, Celine Abueva3, Young-Ki Min1, Hun-Mo Yang2, Byong-Taek Lee3
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| 소속 |
1Department of Biomedical Engineering and Materials and Institute of Tissue regeneration Soonchunhyang Univ., 2Chungnam 330-930, 3Korea |
| 키워드 |
BCP; Gelatin; Collagen; Hyaluronic acid; Chondroitin sulphate; BSA
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| E-Mail |
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