| 초록 |
Dopamine (DA), a neurotransmitter is a chemical courier in the renal, hormonal, cardiovascular, and central nervous systems produced by dopaminergic neurons and controls reward-motivated behavior of the brain. The normal concentration of DA in human serum ranges between 10−7 and 10−3 M, whereas abnormal DA levels causes neurological disorders. Therefore, the sensitive and reliable detection of DA in human serum is essential. In this work, we demonstrated the selective sensing of Dopamine (DA), using Nafion-stabilized Ti3C2Tx MXene. Firstly coated with MXene, glassy carbon electrode was coated with Nafion to achieve a robust sensitivity (~3 nM), good selectivity, wide detection window (0.015–10 µM), high stability, reproducibility, and outstanding recoveries for DA detection in real samples. MXene-based biosensor exhibited much better electrochemical performance compared with reduced graphene oxide-based biosensor under same experimental conditions. |
