| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 봄 (04/08 ~ 04/09, 대전컨벤션센터) |
| 권호 |
35권 1호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Use of photo-patterned polymeric microparticles with SU-8 photoresist to create “shape-coded cell array” |
| 초록 |
Cell-based assays are increasingly being used in drug discovery and single-cell analysis. Recently, to move toward assay miniaturization, significant efforts have focused on the fabrication of cell microarray using a variety of cell patterning techniques photolithography or softlithography. Cell microarrays can be classified into two general categories: chip-based planar array & particle-based suspension arrays. Although chip-based planar arrays have been widely used, suspension arrays are becoming popular as an alternative approach due to advantages over planar array. In this study, we prepared suspension microarrays of cells using various shape of SU-8 microparticles and demonstrate the potential use of this system for multiplexed cell-based assay. Capability of controlling the shapes of microparticles opened the possibility of producing shape-coded suspension array, which can offer a cost-effective and versatile platform for high-throughput and multiplexed cell-based assay. |
| 저자 |
남승희, 이열, 박상필, 장은지, 박새미, 이현종, 손경진, 이영민, 박영하, 고원건
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| 소속 |
연세대 |
| 키워드 |
cell-based assay; SU-8 photoresist; cell patterning; microparticles
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| E-Mail |
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