초록 |
Simulated moving bed chromatography(SMB) is a separation process widely used in chemical industry and pharmaceutical field. In order to overcome the disadvantages of the existing chromatography process, the effect of continuous process is simulated by continuously changing the role of many fixed bed columns. On the other hand, SMB has periodic characteristics, which makes it difficult to analyze features in steady state. In addition, SMB is just simulating the effects of the continuous process, it is more complex than the conventional continuous process and has several differences. Therefore, in this poster, the cyclic discrete dynamic linear model is derived based on the existing SMB modeling equations and the validity is verified by comparing with simulation result. For the future works, we plan to carry out studies to control disturbance factors and diagnose abnormalities in various situations by using the model. |