| 학회 |
한국고분자학회 |
| 학술대회 |
2006년 봄 (04/06 ~ 04/07, 일산킨텍스) |
| 권호 |
31권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Biological Evaluation of NIH/3T3 cells on Low Density Polyethylene Film with Corona Treatment |
| 초록 |
The adhesion and proliferation of cells on polymeric biomaterials depend on the surface characteristics such as wettability, chemistry, charge and roughness. The modified LDPE surfaces were characterized by measuring the static water contact angle. The cells adhered, grown on the microgrooved surfaces were observed by scanning electron microscope (SEM) and Microscope. Also the evaluation of mRAN expression of cells contacting with PE film by reverse transcription-polymerase chain reaction (RT-PCR) analysis. As the surface wettability increased, that is moderate hydrophobic positions, the number of the cell adhered and proliferated on the surface was increased and specific gene showed maximum expression. In conclusion, this investigation demonstrated that the surface wettability of polymer as the PE film plays an important role for cell adhesion and proliferation behavior for biomedical application. Acknowledgement : This study was supported by KMOICE (N11-A08-1402-05-1-3) |
| 저자 |
김선경1, 조미희1, 조영호1, 신유나1, 김문석1, 강길선2, 이해방1
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| 소속 |
1한국화학(연), 2전북대 |
| 키워드 |
Corona discharge; Cell. PCR
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| E-Mail |
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