화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2006년 가을 (11/10 ~ 11/11, 경희대학교(수원캠퍼스))
권호 10권 2호
발표분야 고분자
제목 Ligand-mediated Nanoparticles for Tumor-targeted Drug Delivery System
초록 Drug targeting to a specific organ or tissue selectively and quantitatively would not only improve therapeutic efficiency but also enable a reduction of the amount of drug that must be administered to achieve a therapeutic response, thus minimizing negative side effects. We focused on the development of a ligand-mediated polymeric nanoparticle system for anticancer drug delivery with both a passive targeting property through a size effect, and an active targeting activity through specific recognition of ligand. The main objective of this study is to investigate the feasibility of biotin-conjugated nanoparticle as a ligand-mediated drug carrier for anticancer drugs.
저자 김소연1, 조승혜2, 이영무2
소속 1요업(세라믹)기술원, 2한양대
키워드 Drug delivery system; nanoparticle; ligand; anticancer therapy
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