초록 |
The glucose level is an important issue for the patients with diabetes, and thus the selective and efficient detection of glucose is critical. An effective, reversible, and reusable probe for glucose monitoring still remains a challenge. A new hydrogel sensor based on a copolymer was developed. The copolymer consisted of fluorescent monomers of fluorescein and rhodamine B with a backbone of acrylamide or N-isopropylacrylamide, in which glucose oxidase (GOx) was immobilized on the resultant hydrogel and showed effective fluorescence-sensing performance toward glucose. Upon exposure to glucose, the sensing hydrogel induced visual changes in fluorescence colors that could be identified by the naked-eye. This work provides a facile and promising strategy for constructing a stable, naked-eye-detectable optical protocol that offers sensor reusability for glucose detection. |