| 학회 |
한국화학공학회 |
| 학술대회 |
2020년 가을 (10/14 ~ 10/16, e-컨퍼런스) |
| 권호 |
26권 1호, p.992 |
| 발표분야 |
복잡유체 계(complex fluid system)에서의 심포지엄(미립자공학부문위원회) |
| 제목 |
Microfluidic Production of Hydrogel Microcapsules with a Thin Oil Layer for Stimuli-responsive Cargo Release |
| 초록 |
We present a hydrogel microcapsule with an intermediate thin oil layer to achieve smart release of a broad range of hydrophilic cargoes triggered via diverse stimuli. A microfluidic method is used to produce triple emulsion droplets (W/O/W/O) with a thin oil layer that separates the innermost aqueous phase from the prepolymer phase, which transforms into a hydrogel shell via UV-induced free radical polymerization. The intermediate oil layer within the hydrogel microcapsule acts as a diffusion barrier, enabling encapsulation of various small cargoes within a porous hydrogel shell until a stimulus is applied to destabilize the oil layer. We show that diverse stimuli including chemical dissolution, mechanical stress, and osmotic pressure can be applied to release the encapsulated cargo on-demand. In addition, osmotic pressure and the hydrogel shell thickness can be independently varied to control the onset time of release as well as the release pattern of multiple cargoes encapsulated hydrogel microcapsule; the release can be either simultaneous or selective. |
| 저자 |
최창형 |
| 소속 |
대구한의대 |
| 키워드 |
droplet microfluidics; encapsulation; triple emulsion; microcapsule; triggered release
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| E-Mail |
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| 원문파일 |
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