| 초록 |
Poly (2-hydroxyethyl methacrylate) (poly(HEMA))-based hydrogels have been studied for application in various fields because of their hydrophilic properties and relatively good mechanical properties. To enhance swelling behavior and cell affinity, in this work, poly ((2-hydroxyethyl methacrylate)-(2-(methacryloyloxy) ethyl trimethylammonium chloride solution)) (poly (HEMA-MAETC)) hydrogel beads were successfully fabricated. With the addition of MAETC as a cationic monomer, the swelling behavior was enhanced with water content, which is 20 (%) higher than that for poly (HEMA). Additionally, the elastic modulus was also 3-fold enhanced. Also, the cell affinity was also enhanced by interaction between the positively charged poly (HEMA-MAETC) beads and negatively charged cell. These charge controlled beads were used as a sensor for TNT detection with a green fluorescent protein (GFP)-producing Escherichia coli (E. coli) which is reactive to the material. |
