초록 |
One of the great goals of science and engineering today is to develop rapid, accurate, and portable diagnostic technologies for the prevention of the acquired immune deficiency syndrome (AIDS). It has been estimated that 30−36 million people globally are living with human immunodeficiency virus (HIV)/AIDS and cannot survive more than two years. In this work, we establish flexible large-scale GM(graphene micropattern) nanobiohybrids with close-packed carboxylated polypyrrole nanoparticle (CPPyNPs) arrays for HIV immunosensor. Notably, it had the lowest detection limit of 1 pM, which is 1−2 orders of magnitude more sensitive than previously reported HIV sensors. Moreover, the flexible GM substrates were integrated with microfluidic channels to improve analytical performance in a living system. |