화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2014년 가을 (10/22 ~ 10/24, 대전 DCC)
권호 20권 2호, p.1588
발표분야 생물화공
제목 Detection of Dopamine on Glassy Carbon Electrode Modified by Using Tyrosinase and Multi-Walled Carbon Nanotube
초록 As a crucial catecholamine neurotransmitter, dopamine (DA) is widely present in both the brain and the peripheral nervous system. In this study, characterization and application of dopamine biosensor, glassy carbon electrode (GCE) modified by tyrosinase and multi-walled carbon nanotube are described using electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV). Research was conducted in three electrode system at room temperature. The working electrode, glassy carbon electrode, has been modified using tyrosinase and multi-walled carbon nanotube. Optimization of experimental variables, such as the influence of the amount of tyrosinase, effect of pH, scan rate and interferences were also investigated. These results indicated that the modified electrode has good potential sensitivity and selectivity for determination of dopamine.
저자 Siti Fauziyah Rahman1, Seok-Hwan Park2, Hyoung-Min Lee1, Jae-Hee Park2, 박돈희1
소속 1Interdisciplinary Program of Graduate School for Bioenergy and Biomaterials, 2Chonnam National Univ.
키워드 Dopamine; Biosensor; Tyrosinase Enzyme; Carbon Nanotube
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