| 초록 |
One-dimensional conducting polymer nanomaterials, including nanorods, nanofibers, and nanotubes, have emerged as promising candidates for the fabrication of biosensors due to the merits such as unique anisotropic electronic properties and facile integration with microcircuits. In this presentation, I describe the demonstration of biosensors using functionalized conducting polymer nanotubes for the specific detection of nonlabeled target molecules. Functionalized polypyrrole (PPy) nanotubes were synthesized via chemical oxidation polymerization using an intrinsically functionalized monomer, pyrrole-3-carboxylic acid, during the polymerization. Versatile bioreceptors were successfully introduced onto the nanotube surface, such as DNA, glucose oxidase, thrombin aptamer, heparin, and human olfactory receptor. Importantly, the PPy nanotubes conjugated with bioreceptors allowed the direct and label-free detection of various target molecules. |
