화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2015년 봄 (04/08 ~ 04/10, 대전컨벤션센터)
권호 40권 1호
발표분야 의료용 고분자 부문위원회 II
제목 Evaluation of Duck's Feet Derived Collagen Scaffolds for Bone Tissue Engineering.
초록 In this study, we carried out the possibility of the application of duck's feet derived collagen from livestock waste for bone tissue engineering. We fabricated 2 and 3% DC sponges and then compared with hydroxyapatite (HAp) coated DC scaffolds. To analyze physical properties and morphology of HAp/DC scaffolds, FT-IR and SEM were conducted. Assays of MTT are carried out to measured the attachment and proliferation of bone marrow stem cell (BMSc) in DC content of HAp/DC composite scaffolds. RT-PCR was performed to confirm the BMSc specific genetic marker. For the immunohistochemistry staining, H&E staining were carried out. Overall, this study shows that HAp/DC scaffold have biocompatibility and good physical properties. Also HAp/DC scaffolds show having the possibility to use it as bone graft materials for tissue engineering application. This research was supported by the Brain Korea 21 PLUS Project, NRF and Technology Commercialization Support Program (KMIFAFF 814005-03-1-HD020).
저자 이선의1, 차세롬1, 김은영1, 송정은1, 박찬흠2, 서동삼3, 강길선1
소속 1전북대, 2한림대, 3세원셀론텍
키워드 Hydroxyapatite; Duck's Feet Collagen; Bone Differentiation
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