| 학회 | 한국고분자학회 |
| 학술대회 | 2004년 가을 (10/08 ~ 10/09, 경북대학교) |
| 권호 | 29권 2호, p.335 |
| 발표분야 | 기능성 고분자 |
| 제목 | Stabilization of resveratrol by crystallizing on the monodisperse cyano-functionalized porous polymeric microspheres |
| 초록 | Resveratrol, a polyphenolic compound found in grapes, has attracted great attentions due to their anti-oxidizing effect, anti-inflammatory and chemo-protective advantage against cancer proliferation.1,2 However, the resveratrol has some drawbacks for a commercialization: a small quantity in the plant, difficult to extract and stabilize in the atmosphere, easy to destruct by sunlight. In this work, the stabilization of resveratrol was carried out on the porous polymer particles for the long-term storage as shown in Figure 1(a). Figure 1(b) exhibits the SEM image of the monodisperse, cyano-functionalized porous poly(St-co-DVB-co-AN) microspheres prepared by seeded polymerization in the presence of toluene as a porogen. The resveratrol was crystallized on the porous polymeric microspheres during the adsorption process as shown in Figure 1(c) since hydrogen bonding between hydroxyl groups of reveratrol and cyano groups of porous particles were created. According to the porosity and the crosslinking degree of porous polymeric microspheres, the stability of adsorbed resveratrol were investigated. In addition, the contents and the crystallinity of resveratrol adsorbed on the porous particles were examined by utilizing a high performance liquid chromatograph (HPLC) and a X-ray diffraction (XRD), respectively. Figure 1. Schematic illustration of hydrogen bonding between cyano groups of porous particles and hydroxyl groups of resveratrol (a); SEM image of monodisperse porous poly(St-co-DVB-co-AN) microspheres (b); SEM image of resveratrol adsorbed on the porous polymeric microspheres (c). Reference 1. V. Filip, M. Plockova, J. Smidrkal, Z. Spickova, K. Melzoch, and S. Schmidt, Food Chem., 83, 585 (2003). 2. Y. Wang, F. Catana, Y. Yang, R. Roderick, and R. B. Breemen, J. Agric. Food Chem., 50, 431 (2002). |
| 저자 | 남정범1, 류지현1, 이종석2, 김진웅2, 서경도1 |
| 소속 | 1한양대, 2태평양 |
| 키워드 | resveratrol; porous microsphere; hydrogen bonding |
