| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 가을 (10/06 ~ 10/07, 김대중 컨벤션센터) |
| 권호 |
36권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Preparation of Sericin-PEG bioconjugate |
| 초록 |
Silk sericin(SS) is a protein that constitutes 25% of cocoon and surrounds the fibroin. Generally SS is removed through a degumming process of silk but reuse of SS will provide a new biopolymer in the materials field. However, due to long-term instability in water, it limits the use of SS for further application. SS has much of active hydroxyl pendent groups originating from serine or tyrosine. We prepared SS-PEG bioconjugate by reacting hydroxyl groups with activated PEG. After that, we analyzed its conformation, structure, shape and self-assembling mechanism. We anticipate that SS-PEG bioconjugate can be used as bioactive materials in drug delivery field. |
| 저자 |
윤해성, 이기훈, 오한진, 김무곤, 곽효원, 이정윤
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| 소속 |
서울대 |
| 키워드 |
sericin; peg; bioconjugate
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| E-Mail |
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