| 학회 |
한국재료학회 |
| 학술대회 |
2014년 가을 (11/27 ~ 11/28, 대전컨벤션센터) |
| 권호 |
20권 2호 |
| 발표분야 |
D. 바이오 재료(Biomaterials) |
| 제목 |
Role of simvastatin loaded nanocellulose-gelatin-TCP hydrogel for enhanced bone regeneration. |
| 초록 |
In this work we report the fabrication and detailed biocompatibility evaluation of simvastatin loaded nanocellulose-gelatin-tricalcium phosphate hydrogel scaffold. Nanocellulose-gelatin-TCP hydrogel was prepared by freeze-drying method and then it was loaded with different concentrations of simvastatin. Material characterization was provided by SEM, micro CT and FTIR. Detailed biocompatibility study was carried out by MTT, Cell proliferation, cell differentiation and implantation in rat skull for 4 and 8 weeks. In vitro biocompatibility and the amount of new bone formation was higher in simvastatin loaded nanocellulose-gelatin-TCP hydrogel scaffold. |
| 저자 |
Mousumi Sukul1, Nguyen Thuy Ba Linh2, ByongTaek Lee3
|
| 소속 |
1Department of Regenerative medicine, 2Soonchunhyang Univ., 3College of Medicine |
| 키워드 |
Nanocellulose; Gelatin; TCP nano particle; simvastatin; bone regeneration
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| E-Mail |
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