화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2009년 봄 (04/15 ~ 04/17, 호텔인터불고(대구))
권호 13권 1호
발표분야 고분자
제목 Biodegradable Poly(aspartic acid) Derivatives Conjugated with various Amino acids for Pharmaceutical and Cosmetic Applications
초록 Novel poly(aspartic acid) derivatives conjugated with various amino acids and their amphiphilic copolymers were synthesized as a materials to be used in pharmaceutical and cosmetics field. Methyl esters of various amino acids were synthesized and used for the aminolysis reaction onto polysuccinimide(PSI). The following hydrolysis process provided the corresponding amino acid-conjugated PASP in high reaction yield. Amino acid conjugated amphiphilic analogs were also prepared by introducing hydrophobic alkyl amine along with amino acid using the similar procedure.
저자 손창모1, 전영실2, 김지흥1
소속 1성균관대, 2고분자기술(연)
키워드 Poly(aspartic acid); amino acid; methyl ester; amphiphilic
E-Mail